On April 30, 1665, Samuel Pepys recorded his first diary entry about the Great Plague of London: "Great fears of the sickness here in the city, it being said that two or three hourses are already shut up. God preserve us all." 354 years later, to the day, officials in Portland, Oregon, are practicing for a plague outbreak
. From April 30 to May 2, emergency responders and public health agencies are rehearsing their response to a simulated bioterrorism attack unleashing Yersinia pestis
on the port city of 650,000. The three-day drill is part of how those agencies ensure that they're prepared to contain an outbreak if (or when) it happens -- which is part of how we keep modern cities from turning in London, circa 1665.